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PROTO-ONCOGENE PROTEINS P21(RAS)
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins p21(ras)
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas p21(ras)
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas p21(ras)
Synonyms
English
:
Proto-Oncogene Proteins c-ras
c-Ha-ras p21
c-Ki-ras p21
p21(c-Ha-ras)
p21(c-Ki-ras)
p21(c-ras)
p21(N-ras)
p21(ras)
ras Proto-Oncogene Protein p21
Tree Number:
D08.811.277.040.330.300.400.500.600
D12.644.360.525.500.600
D12.776.157.325.515.500.600
D12.776.476.525.500.600
D12.776.624.664.700.200
Definition
English
:
Cellular
proteins
encoded by the H-ras, K-ras and N-ras
genes
. The
proteins
have GTPase activity and are involved in
signal transduction
as
monomeric GTP-binding proteins
. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.
See Related
English
:
Costello Syndrome
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29090
Unique Identifier:
D016283
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS